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pentobarbital will decrease the level or impact of dutasteride by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.pentobarbital will lower the extent or effect of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of fentanyl with CYP3A